Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

Allison McClure, Ph.D., is an assistant professor in the Department of Biochemistry and Molecular Genetics at the CU School of Medicine. She is focused on learning all about how cells replicate, or ...

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...

A new, nano-scale look at how the SARS-CoV-2 virus replicates in cells may offer greater precision in drug development, a Stanford University team reports in Nature Communications. Using advanced ...

ELF3 axis enables luminal progenitor transformation in BRCA1-deficient breast cancer by reducing genomic instability and promoting progenitor identity.

Adeno-associated virus (AAV) vectors play a pivotal role in gene therapy, delivering therapeutic genes with high precision and safety. However, a significant challenge in the biomanufacturing of these ...

A research team has developed a new RNA-based system that can detect coronavirus infection in real time inside living cells—and even trigger antiviral responses only when infection occurs.

A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...