The research team has shown that a transcriptional co-activator ANGUSTIFOLIA3 (AN3) forms a signaling gradient along the leaf proximal-to-distal axis to determine cell-proliferation domain. In an ...

New work describes vital aspects of diffusion processes in tissue development, including the roles that molecular diffusion gradients have on stem cell signaling pathways along with new modeling tools ...

A morphogen is a type of signalling molecule that imparts pattern to a developmental field by acting directly on cells in a concentration-dependent manner. The best-studied model system for ...

Gradients of molecular signaling factors play an essential role in numerous events in embryonic development, from patterning limb and organ formation to the intricate shaping of the brain and ...