The complement system in teleost fish constitutes a cornerstone of innate defence, integrating classical, lectin and alternative activation routes to eliminate pathogens and shape inflammatory ...

Complement 3 glomerulopathy (C3G) is a rare kidney disease that affects your body’s innate immune system (complement system). Complement 3 glomerulopathy (C3G) is a kidney disease that’s caused by ...

The complement system, a key component of innate immunity, exerts profound influence on the initiation, progression and destabilisation of atherosclerotic plaques. Activation may proceed via the ...

Innate lymphoid cells, which curiously behave like T cells even though they don’t recognize specific antigens, show promise as a potential cancer therapeutic. In the years that followed, other groups ...

Researchers have shown that innate immune training, also known as trained immunity (TRIM), leads to aggravated bone loss in experimental models of periodontitis and inflammatory arthritis. Clinical ...

Researchers have discovered that mRNA-based COVID-19 vaccines have a persistent effect on the innate immune system. These mechanisms may help the human body to better protect itself against potential ...

Our immune system is divided into two main branches: innate and adaptive. Innate immune cells act as a first line of defense, quickly responding to invaders, while adaptive immune cells take a longer ...

Unlike transient innate immune activation, trained immunity is characterized by long-lasting but reversible functional reprogramming of monocytes, macrophages, natural killer (NK) cells, and ...

Dozens of new discoveries reveal that defenses evolved by bacteria and viruses billions of years ago still define our own innate immune system. Evolutionary arms races — where one species is pitted ...

Antibodies, which recognize viruses and proteins that the body has encountered before, have long gotten most of the credit for giving the human immune system a memory. Now, researchers at the ...